Our 10 Best Itching Cream in the UK - May 2025 (2025)

9.9 Comfort

9.7 Simple to use

8.9 worth the money

Main highlights

• Perfume Free
• Dermatologically Tested
• Allergy Screened

Main highlights

• 【Wide Application】iShanCare anti-itch cream is highly recommended by dermatologists and it will not irritate your skin. Our anti itch cream is safe for whole body to use, you can apply to affected areas 1-3 times daily and soon all the discomfort will disappear.
• 【Natural, Mild & Safe Ingredients】iShanCare itch cream boasts mild ingredient that works wonder on relieving itching without causing discomfort. Our itching cream can also deliver great soothing action for dry skin, sensitive skin, redness, irritation, swelling, inflammation.
• 【Instant & Long Lasting Relief】iShanCare anti itch cream has been clinically proven to provide fast relief from itching due to rash, eczema, bug/mosquito bites, psoriasis, poison ivy, dermatitis, poison oak, sumac, soaps, detergent, jewelry, clothes with static electricity, dry weather. After 90 seconds of application, you can feel remarkable itch relief.
• 【Easy to Absorb & Moisturizing】iShanCare maximum strength anti-itch cream can be absorbed into the skin within 15 seconds, it will leave no residue after use. When applied to the skin, our itch relief cream will penetrate quickly, locks in moisture, thus maintaining the moisture balance of your skin.
• 【100% Quality Guarantee】Within 365 days from the date of purchase, we will provide replacement products or refund services unconditionally. If you have any questions about the iShanCare itch cream, please feel free to contact us.

9.7 Simple to use

9.1 worth the money

9.1 Comfort

Main highlights

• TREAT ITCHING AND SKIN IRRITATION – E45 Itch Relief Cream is a dual action treatment for skin irritation and itching caused by dry skin conditions, eczema, dermatitis, pruritus, and scaling skin conditions
• QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. It has proven dermatological expertise dedicated to vulnerable dry skin
• MOISTURISING AND ANTI-ITCH INGREDIENTS – E45 Itch Relief Cream is formulated with urea which helps your skin to retain moisturise and keeps it hydrated. With the skin less itchy, you will scratch less and therefore speed up the healing process
• HOW TO USE – Apply to the affected skin area twice daily for effective relief for itching and skin irritation. Our cream is perfume free can be used in all skin areas such as the body, face, and hands
• HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 our cream was introduced to pharmacy and retail in 1980

Main highlights

• VERSATILE APPLICATION FOR VARIOUS SKIN CONDITIONS: Whether you're dealing with mosquito bites, poison ivy, or dry, irritated skin, this Cream is a versatile solution for itching relief. Its multi-purpose design makes it suitable for use on a wide range of skin conditions, providing targeted relief wherever you need it most.
• TRUSTED BY FAMILIES FOR GENERATIONS: A trusted brand with a legacy of providing effective relief for itching and irritation. For generations, families have turned to this Cream for its reliable performance and soothing properties, making it a staple in any first aid kit or medicine cabinet. With this rapid relief Cream, you can trust that you're using a product that prioritizes your skin health and well-being.
• SOOTHES AND CALMS IRRITATED SKIN: Formulated with skin-calming ingredients, this Cream not only relieves itching but also helps to soothe and calm irritated skin. By reducing redness and inflammation, it promotes skin comfort and restores a sense of tranquillity to your complexion.
• RAPID ACTION FORMULA FOR PROMPT RELIEF: Featuring a fast-acting formula, this Cream works quickly to alleviate itching, providing prompt relief when you need it most. Its rapid action helps to quell the urge to scratch, preventing further irritation and allowing your skin to heal more effectively.
• LONG-LASTING ITCH RELIEF FOR EXTENDED COMFORT: This Rapid Relief Cream doesn't just offer temporary relief—it provides long-lasting comfort that lasts for hours. Its enduring effects ensure continuous relief from itching, allowing you to go about your day without the discomfort of persistent itching and irritation.
• EFFECTIVE RELIEF FROM ITCHING AND IRRITATION: This Cream is your go-to solution for effective relief from itching and irritation caused by a variety of skin conditions, including insect bites, eczema, dermatitis, and allergic reactions. By targeting the root cause of itching, this cream offers soothing comfort and relief, allowing you to enjoy smoother, more comfortable skin.

9.9 Simple to use

9.9 Easy to use

9.9 worth the money

Main highlights

• Handmade in the UK, using simple yet effective ingredients expertly selected to help your skin instantly.
• Delicately blended with lavender oil for a subtle scent.
• Calm & Calamine UK have been formulating Traditional Calamine Cream for over 50 years!
• Calamine is one of the best ingredients for soothing irritations.
• A rich and calming cream to help relieve the pain and irritation from itching, spots, rashes and bites.

9.1 Simple to use

9.1 Comfort

8.7 worth the money

Main highlights

• With an easy to use applicator prefilled with a single dose of internal cream to clear the internal infection, this pack also comes with double strength* thrush external cream to treat your uncomfortable external symptoms. *Compared with Canesten 1 percent Cream.
• This soothing combination treatment targets both the internal cause and external symptoms of vaginal thrush for a complete relief
• This pack includes a single dose of internal cream in a pre-filled applicator and one 10-gram tube of external cream. Always read the label.
• Apply the internal cream with the help of the applicator before going to sleep at night for convenient and comfortable treatment. Gently smooth the external cream on the affected area 2-3 times daily until symptoms disappear.
• A 2-step solution to calm the itch and clear the infection for a complete relief

Main highlights

• Versatile Formulation
• Relief from Itching
• Anti-Inflammatory Action

Main highlights

• VERSATILE USE: Effectively treats multiple skin conditions including rashes, insect bites, hives, eczema symptoms, and general skin redness
• SKIN-FRIENDLY FORMULA: Non-greasy, fast-absorbing cream leaves no sticky residue and won't stain clothing
• FAST RELIEF: Non-prescription cream provides quick soothing relief from itching, allergic reactions, and skin irritations within minutes of application
• EASY APPLICATION: Simply apply a thin layer to affected areas up to 3-4 times daily for optimal relief from itching and discomfort
• CONVENIENT SIZE: 25g tube is perfect for home medicine cabinets or travel, allowing for multiple applications when needed

Main highlights

• 【USED AS AN EMOLLIENT】Relieves dry skin conditions prone to flare-ups such as eczema and psoriasis, soothes dry skin and dermatitis caused by frequent hand washing or use of alcohol-based hand sanitizers and gels, by forming effective dry barrier to moisturize and help repair skin.
• 【SAFE】Organic herbal eczema treatment cream, using excellent natural plant formula, fragrance-free, skin-friendly, refreshing feeling makes you feel better. It can relieve skin itching, inhibit fungal infection, eczema, peeling, itchy feet, etc.
• 【HOW TO USE】This product is 100g. 1. Wash the skin before use; 2. Take an appropriate amount of moisturizing cream and apply it to the skin; 3. Keep using it to make the skin smoother and more tender.
• 【HELPS MOISTURIZE SKIN】Our skin moisturizer soothes and cares for the skin and is designed to help relieve dry, flaky skin. Make your skin smoother. Soothing and caring for the skin, our herbal formula is designed to help relieve itching associated with rashes, minor skin irritations, eczema and inflammation caused by psoriasis.
• 【FAST AND EFFECTIVE】This slows down the production of skin cells, relieves pain, reduces itching, moisturizes damaged areas of skin, repairs and restores skin elasticity, can strengthen the skin's natural barrier against irritants and natural harsh elements, making it easier to prevent skin problems relapse.